Gastric Cancer Surgery in Elderly Patients

Completed

• Conditions: Gastric Cancer
• Interventions: Procedure: Gastric resection

• Registration Number: NCT03777540
• Lead Sponsor: University of Bologna

Brief Summary

Gastric cancer is most frequent after the fifth decade of life. Surgical risk is higher in aged population because of general health condition may affect the postoperative result. Aim of the study was to identify risk factors for post-operative mortality in octogenarian patients who underwent surgery for gastric cancer.

Detailed Description

236 patients (181: 80-85 years old and 55: \>85 years old) underwent surgery for gastric cancer at the Sant'Orsola-Malpighi University Hospital in Bologna between 2010 and 2015. The variables of the two groups of patients were compared.

Study Timeline

• Study Start: 2010-01-01
• Primary Completion: 2015-12-31
• Study Completion: 2018-06-30
• Status Verified: 2018-12
• Study First Submitted: 2018-12-07
• Study First Submitted QC: 2018-12-14
• Last Update Submitted: 2018-12-14
• Study First Posted: 2018-12-17
• Last Update Posted: 2018-12-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 236

Inclusion Criteria

• Patients with histologically confirmed primary gastric cancer submitted to surgical treatment;
• Age > 80 years.

Exclusion Criteria

• Patients with histologically confirmed primary gastric cancer submitted to surgical treatment and age < 80 years;
• Patients with histologically diagnosis of other neoplastic and non-neoplastic diseases submitted to surgical treatment.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Age; timing of gastric resection	Gastric resection	Patients 80-85 years; Patients \> 85 years; Elective and urgent surgery.

Primary Outcome Measures

Name	Time	Method
Post-operative mortality In-hospital mortality was defined that occurred during hospitalization up to 90 days excluded post-operative mortality. Postoperative mortality	Up to 90-days	mortality occurred up to 90 days from surgery

Secondary Outcome Measures

Name	Time	Method
Overall survival	Up to 5-years	Overall survival was defined as the time from the date of surgery to patient death (including surgery-associated death or hospital death), or the date of last available information concerning vital status.