The predictive relevance of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and mean platelet volume for the diagnosis of complicated acute appendicitis

Completed

• Conditions: Biomarkers; Complicated appendicitis; Appendicitis; Leukocyte Counts; Emergencies

• Registration Number: TCTR20230405006
• Lead Sponsor: /A

Brief Summary

eutrophil at 83% and neutrophil-to-lymphocyte ratio (NLR) at 7.4 have predictive value in the diagnosis of CA. Furthermore, CA patients had a significantly longer length of stay (4.67 days versus 2.29 days) but there was no significant difference in operative time or postoperative complication rate.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-03-31
• Study Start: 2023-04-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 369

Inclusion Criteria

Acute appendicitis patients who underwent appendectomy procedures between January 1, 2016, and March 31, 2022.

Exclusion Criteria

patients with advanced age, pregnancy, atherosclerotic disease, diabetes mellitus, hematologic disease, or use of steroids or immunosuppressants, any of which can affect serum biomarker interpretation.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
predictive value of simple CBC biomarkers such as WBC, neutrophils, NLR, PLR, and MPV in the diagnosis of complicated appendicitis At 2 weeks after surgery Accuracy of biomarkers in diagnosis of complicated appendicitis

Secondary Outcome Measures

Name	Time	Method
Postoperative outcomes At 2 week after surgery Postoperative complication rate