Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention

Completed

• Conditions: Femoral Neck Fracture; Infection
• Interventions: Procedure: Hip arthroplasty

• Registration Number: NCT02771639
• Lead Sponsor: Sundsvall Hospital

Brief Summary

Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF). Debridement, antibiotics and implant retention (DAIR) is recommended in early PJI in association with stable implants. Few studies have evaluated the outcome of DAIR in this fragile population.The purpose of this study was to analyze risk factors for PJI and the short-term outcome of DAIR in FNF patients treated with a hip arthroplasty.

Methods A consecutive series of patients had been treated with either a total hip arthroplasty or a hemi hip arthroplasty for a displaced FNF at our institution. Data were retrospective analysed.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Status Verified: 2016-05
• Primary Completion: 2016-05
• Study Completion: 2016-05
• Study First Submitted: 2016-05-08
• Study First Submitted QC: 2016-05-12
• Last Update Submitted: 2016-05-12
• Study First Posted: 2016-05-13
• Last Update Posted: 2016-05-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 736

Inclusion Criteria

• Displaced femoral neck fracture
• Treated with a primary hip arthroplasty

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Femoral neck fractures	Hip arthroplasty	Patients admitted to Sundsvall hospital for a displaced femoral neck fracture and treated with a hip arthroplasty

Primary Outcome Measures

Name	Time	Method
Rate of periprosthetic joint infection	1 year	The incidence of periprosthetic joint infection

Secondary Outcome Measures

Name	Time	Method
The rate of healed periprosthetic joint infections after treatment with surgical debridement.	6 months	The rate of healed periprosthetic joint infections after treatment with surgical debridement.