DRKS00010559
Recruiting
N/A
Plasticity in brain circuits underlying interactions between pain and depression
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- F33
- Sponsor
- Zentralinstitut für Seelische Gesundheit (ZI)
- Enrollment
- 250
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •For all subjects:
- •\- Sufficient german language abilities
- •\- Ability to consent
- •\- Residence in Mannheim or within a 50 km radius
- •For healthy controls
- •\- No diagnosis of any psychiatric disorder according to ICD\-10 and DSM\-IV
- •\- No family history of any psychiatric disorder according to ICD\-10 and DSM\-IV
- •For healthy first grade relatives:
- •\- No diagnosis of any psychiatric disorder according to ICD\-10 and DSM\-IV
- •\- First grade relative of patients with the diagnosis of MD according to ICD\-10 or DSM\-IV
Exclusion Criteria
- •Exclusion Criteria:
- •\- Participant unable to content
- •\- Acut exacerbated psychosis or psychiatric comorbidity, which needs clinical or pharmacological treatment
- •\- Change in psychopharmacological treatment in the last 8 weeks
- •\- Substance abuse except for nicotine
- •\- For healthy controls and first degree relatives: psychiatric disorder according to ICD\-10 or DSMIV
- •For the stepwise procedure additional exclusion criteria for the MRI:
- •\- For women: pregnancy
- •\- MR exclusion criteria (e.g. claustrophobia, pacemaker, artificial heart valves, cochlear implants, intracranial vessel clip, metal implants, brain surgery, permanent makeup, large scale tattoos on head or nape)
Outcomes
Primary Outcomes
Not specified
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