Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy in Solid Pancreatic Masses
- Conditions
- Solid Pancreatic Masses
- Registration Number
- NCT02936960
- Lead Sponsor
- Shandong University
- Brief Summary
The differential diagnosis of solid pancreatic masses by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is currently suboptimal. Needle-based confocal laser endomicroscopy (nCLE) is a novel endoscopic technique, which is compatible with the 19-gauge FNA needle. Under endoscopic ultrasonography (EUS) guidance, nCLE enables real-time in vivo imaging of lesion tissues at cellular and subcellular levels. This study aimed to describe nCLE interpretation criteria for the characterization of pancreatic masses, with histopathological correlation, and to perform the validation of these criteria.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- patients with any pancreatic mass
Exclusion Criteria
- Patients aged <18 years or >80 years
- Known allergy to fluorescein dye
- Previous EUS-FNA performed within the past 3 months, and usualcontraindications to EUS-FNA
- Pregnancy or breastfeeding
- Inability to provide informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The nCLE interpretation criteria for the characterization of pancreatic masses with histopathological correlation 20 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Gastroenterology, Qilu Hospital, Shandong University
🇨🇳Jinan, Shandong, China