Rotational Thromboelastometry Guided Transfusion Protocol versus Classical Transfusion Protocol in Reducing Blood Components Transfusion in Adult Patients Undergoing Elective Cardiac Surgery
Phase 2
- Conditions
- Anaesthesia
- Registration Number
- PACTR202402769956111
- Lead Sponsor
- Suez Canal University Teaching Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Patients undergoing elective primary cardiac surgery on cardiopulmonary bypass (coronary artery bypass graft, valve replacement or coronary artery bypass graft with valve replacement)
- ASA II or III
- More than 18 years-old (both sexes)
Exclusion Criteria
- Emergent cardiac surgeries.
- Re-do cardiac surgeries.
- Patients taking oral anticoagulants within 5 days of surgery or low molecular weight heparin until the day of surgery.
- Patients with congenital or acquired coagulopathy.
- Patients with impaired liver functions (elevated liver enzymes)
- Patients with impaired renal functions (serum creatinine > 2 mg/dL)
- Patients with body mass index < 18 kg/m2 or > 35 kg/m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-bypass blood components transfusion requirements.;Postoperative blood components transfusion requirements
- Secondary Outcome Measures
Name Time Method Postoperative blood loss measured as chest tube drainage after exclusion of surgical cause of bleeding;Detecting residual heparin after its reversal with protamine