Research of the Different Treatments for Chronic Pain Patients, Their Effectiveness and Associated Predictors, Offered at the Pain Center AZ Sint-Lucas Ghent.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- University Ghent
- Enrollment
- 1,000
- Locations
- 1
- Primary Endpoint
- Change in Pain intensity from baseline until 18 months
Study Overview
Brief Summary
The goal of this observational study is to compare different treatment options in a chronic pain population. The main questions it aims to answer are:
- What is the effectiveness of the different therapy options in the pain center of Sint-Lucas on outcomes related to pain and disability?
- What are predictive factors for the different therapy options in the pain center of Sint-Lucas? Which factors predict improvement in pain related outcomes?
Participant data will be gathered as part of their routine care. They can be advised to 4 different treatment options:
- Consultations with the pain specialist
- Interventions by the pain specialist (infiltrations, denervations)
- Baxter therapy
- Interdisciplinary treatment
Researchers will compare patients with different dominant pain mechanisms to see which treatment are most effective for which dominant pain mechanisms.
Detailed Description
The aim of the present study is to describe the natural flow of the chronic pain patients at the pain center AZ Sint-Lucas. Patients will be examined before starting the therapy, and receive standardized questionnaires at several fixed time points (before, during, and after their therapy trajectory). Information about the present dominant pain mechanism will be gathered during the examination. The questionnaires will gather demographic data, information about the present dominant pain mechanism, psychosocial factors, catastrophizing, fear and avoidance, illness perceptions, fatigue and information about therapy success. During the examination, typical signs of a dominant nociplastic pain mechanism will be gathered. By processing the data of the questionnaires and the examination, knowledge about (1) the amount of patients with a dominant nociplastic pain mechanism at intake, (2) the treatment trajectory for a specific diagnosis, and (3) the prediction of the therapy effect and prognosis will be obtained.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Chronic pain patients
- •Dutch speaking, or good understanding
Exclusion Criteria
- •Adults unable to give consent
- •Adults who do not understand Dutch
Arms & Interventions
Chronic pain patients
Chronic pain patients with a dominant nociceptive pain mechanism, a dominant neuropathic pain mechanism and a dominant nociplastic pain mechanism. They will receive different treatments: Consultations, Interventions (injections, denervations...), Baxter therapy and interdisciplinary treatment.
Intervention: Consultation (Other)
Chronic pain patients
Chronic pain patients with a dominant nociceptive pain mechanism, a dominant neuropathic pain mechanism and a dominant nociplastic pain mechanism. They will receive different treatments: Consultations, Interventions (injections, denervations...), Baxter therapy and interdisciplinary treatment.
Intervention: Interventions (Procedure)
Chronic pain patients
Chronic pain patients with a dominant nociceptive pain mechanism, a dominant neuropathic pain mechanism and a dominant nociplastic pain mechanism. They will receive different treatments: Consultations, Interventions (injections, denervations...), Baxter therapy and interdisciplinary treatment.
Intervention: Baxter therapy (Drug)
Chronic pain patients
Chronic pain patients with a dominant nociceptive pain mechanism, a dominant neuropathic pain mechanism and a dominant nociplastic pain mechanism. They will receive different treatments: Consultations, Interventions (injections, denervations...), Baxter therapy and interdisciplinary treatment.
Intervention: Interdisciplinary therapy (Behavioral)
Outcomes
Primary Outcomes
Change in Pain intensity from baseline until 18 months
Time Frame: 0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months
Numeric Rating Scale for pain intensity in the past week, ranges from zero to 100, with a higher score indicating a higher pain intensity
Change in Pain Frequency from baseline until 18 months
Time Frame: 0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months
Questions
Change in Functionality from baseline until 18 months
Time Frame: 0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months
Patient Specific Complaints questionnaire, using a Numeric Rating Scale, ranging from zero to 100, with a higher score indicating a higher amount of functional disability
Change in Quality of Life from baseline until 18 months
Time Frame: 0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months
EuroQol-5D questionnaire
Change in Pain disability from baseline until 18 months
Time Frame: 0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months
Pain Disability Index, ranges from zero to 70, with a higher score indicating more pain-related disability
Secondary Outcomes
- Change in Quality of Life from baseline until 18 months(0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months)
- Change in Post exertional malaise from baseline until 18 months(0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months)