Evaluation of effects of Persian Gulnar on bleeding in patients with leiomyoma of uterus

Phase 2

Conditions: Leiomyoma of uterus
eiomyoma of uterus.

Registration Number: IRCT2013120715703N1

Lead Sponsor: School of Traditional Medicine Traditional Medicine and Materia Medica Research Center Shahid Behesh

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 10

Inclusion Criteria

1) Age: 18-50 years 2) Ultrasound evidence of uterine leiomyoma (submucosal leiomyoma, intramural leiomyoma, subserosal leiomyoma). 3) History of abnormal menstrual bleeding based on the patient's complaint. Exclusion Criteria 1) Indication of uterine surgery (except Caesarean section or cervical conization). 2) Patients receiving progesterone, acetyl salicylic acid anticoagulant. 3) Patients with a positive pregnancy test. 4) History of allergy to Persian Gulnar. 5) Known hemoglobinopathies. 6) Known severe coagulation disorder. 7) Patients receiving Anti-fibrinolytic. 8) Hemoglobin below 9.5. 9) Ultrasound evidence of hyperplasia of the endometrium.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Menstrual blood volume. Timepoint: Before the intervention, weeks 5, 9, 13 after intervention. Method of measurement: Pictorial Blood Loss assessment Chart (PBAC).;Quality of life that is evaluated by Menorrhagia Questionnaire (MQ). Timepoint: Before the intervention, weeks 13 after intervention. Method of measurement: Quality of life that is evaluated by Menorrhagia Questionnaire (MQ).;The size of leiomyoma. Timepoint: Before the intervention, weeks 13 after intervention. Method of measurement: ultrasound.

Secondary Outcome Measures