Treatment Outcome of Children With HIV Infection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 500
- 试验地点
- 3
- 主要终点
- 1. To collect clinical and immunologic data of children treated with HAART 2. To collect clinical outcome data on children with HIV infection 3. To provide the best possible care to children with HIV infection
研究概览
简要总结
To evaluate clinical and immunological outcome of children treated with HAART.
详细描述
This is a long term cohort study that was started in 2002. Currently, there are 120 children enrolled in the study and are receiving HIV care according to standard practice set by the Thai Ministry of Public Health. HIV-infected parents also receive care at the same clinic.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 20 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children who are part of the ATC program at Chulalongkorn hospital and at HIV-NAT, The Thai Red Cross AIDS research center
- •Children who fulfil criteria to start HAART according to the ATC program
- •Children who are switched to second regimen or salvage therapy
- •Children who are on any antiretroviral regimens, including post trial children from other HIV-NAT study (both at HIV-NAT and Khon Kaen University sites)
- •Children with HIV infection who are not on antiretroviral therapy
- •Caretakers understand the purpose of data and plasma samples collection, and have signed the consent form
排除标准
- •Patients and caretakers may choose to stop HAART at anytime during the study. If they agree, we would continue to follow them in this study.
研究组 & 干预措施
Long-term pediatric cohort
Long-term follow-up cohort since 2003
干预措施: Zidovudine, Stavudine, Didanosine, Lamivudine (Drug)
Long-term pediatric cohort
Long-term follow-up cohort since 2003
干预措施: Nevirapine, Efavirenz (Drug)
Long-term pediatric cohort
Long-term follow-up cohort since 2003
干预措施: LPV/r, Saquinavir, Indinavir, Ritonavir, Nelfinavir (Drug)
结局指标
主要结局
1. To collect clinical and immunologic data of children treated with HAART 2. To collect clinical outcome data on children with HIV infection 3. To provide the best possible care to children with HIV infection
时间窗: every 3 months
次要结局
未报告次要终点