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Clinical Trials/NCT05748327
NCT05748327
Active, not recruiting
Not Applicable

Randomized Controlled Clinical Trial (RCT) of the New Tooth-colored Restorative Material 'Cention Forte' (Ivoclar Vivadent) vs. 'Equia Forte HT' (GC) in Class-I/II Cavities

Ivoclar Vivadent AG1 site in 1 country58 target enrollmentNovember 22, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Caries
Sponsor
Ivoclar Vivadent AG
Enrollment
58
Locations
1
Primary Endpoint
Success Rate
Status
Active, not recruiting
Last Updated
2 years ago

Overview

Brief Summary

This is a randomized-controlled clinical trial to investigate the success rate of two new tooth-colored restorative materials in class I and II cavities over 5 years according to FDI criteria scores (1, 2 and 3).

Detailed Description

The primary outcome of the study is the SUCCESS RATE of restorations placed with both filling materials in class I and II cavities after 5 years of clinical service. A failure which leads to repair or replacement of the restoration can have esthetic (marginal staining, loss of anatomical form), functional (i.e. fracture of restoration, loss of retention) or biological reasons (i.e. secondary caries). A restoration is defined as a failure (no success) as soon as at least one FDI criterion is scored as 4 or 5.

Registry
clinicaltrials.gov
Start Date
November 22, 2022
End Date
April 1, 2028
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Subject's age between 18 and 65 years old
  • Class I and Class II (with a cavity margin 1-1.5 mm from the cusp tip) (caries treatment, removal of existing defective amalgam/composite restorations), on premolars/molars
  • Vital teeth
  • 2 restorations per patient: both cavities should have comparable size and dimensions
  • Presence of neighbour tooth and antagonist (molars with no neighbour tooth at the distal side can also be included)
  • Low to moderate caries rate/normal periodontal status with good home care

Exclusion Criteria

  • Hospitalized and medically compromised patients (medical history may not compromise the outcome of the results)
  • Pulp exposure or signs of pulpal infection
  • No signs of pulpitis or hypersensitivity (Visual analog scale \< 3 on biting and temperature sensitivity)
  • History of allergy to glass ionomer, acrylate/methacrylate monomers
  • Pregnancy
  • Chronic disease with oral manifestations or primary oral pathology
  • Bad oral hygiene
  • High caries rate or periodontal problems
  • Absence of antagonists
  • Absence of adjacent teeth (except last molar in the row with no neighbour tooth at the distal side)

Outcomes

Primary Outcomes

Success Rate

Time Frame: 5 years

assessed following FDI criteria on a scale from 1 "very good" to 5 "unacceptable": e.g. post-operative hypersensitivity, surface lustre, staining, fracture of material, retention, occlusal contour and wear, and colour match of restorations (Success: Scores equal to/above 3)

Secondary Outcomes

  • Survival Rate(6 months to 5 years)
  • Success Rate(6 months to 3 years)
  • Quality criteria (Clinical performance)(6 months to 5 years)

Study Sites (1)

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