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Trial With Two New Tooth-colored Restorative Materials in Class I/II Cavities

Not Applicable
Active, not recruiting
Conditions
Caries
Defective Restorations
Interventions
Device: Bulk fill glass hybrid restorative material
Device: Alcasite restorative material
Registration Number
NCT05748327
Lead Sponsor
Ivoclar Vivadent AG
Brief Summary

This is a randomized-controlled clinical trial to investigate the success rate of two new tooth-colored restorative materials in class I and II cavities over 5 years according to FDI criteria scores (1, 2 and 3).

Detailed Description

The primary outcome of the study is the SUCCESS RATE of restorations placed with both filling materials in class I and II cavities after 5 years of clinical service. A failure which leads to repair or replacement of the restoration can have esthetic (marginal staining, loss of anatomical form), functional (i.e. fracture of restoration, loss of retention) or biological reasons (i.e. secondary caries). A restoration is defined as a failure (no success) as soon as at least one FDI criterion is scored as 4 or 5.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
58
Inclusion Criteria
  • Subject's age between 18 and 65 years old
  • Class I and Class II (with a cavity margin 1-1.5 mm from the cusp tip) (caries treatment, removal of existing defective amalgam/composite restorations), on premolars/molars
  • Vital teeth
  • 2 restorations per patient: both cavities should have comparable size and dimensions
  • Presence of neighbour tooth and antagonist (molars with no neighbour tooth at the distal side can also be included)
  • Low to moderate caries rate/normal periodontal status with good home care
Exclusion Criteria
  • Hospitalized and medically compromised patients (medical history may not compromise the outcome of the results)
  • Pulp exposure or signs of pulpal infection
  • No signs of pulpitis or hypersensitivity (Visual analog scale < 3 on biting and temperature sensitivity)
  • History of allergy to glass ionomer, acrylate/methacrylate monomers
  • Pregnancy
  • Chronic disease with oral manifestations or primary oral pathology
  • Bad oral hygiene
  • High caries rate or periodontal problems
  • Absence of antagonists
  • Absence of adjacent teeth (except last molar in the row with no neighbour tooth at the distal side)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Bulk fill glass hybrid restorative materialBulk fill glass hybrid restorative material-
Alcasite restorative materialAlcasite restorative material-
Primary Outcome Measures
NameTimeMethod
Success Rate5 years

assessed following FDI criteria on a scale from 1 "very good" to 5 "unacceptable": e.g. post-operative hypersensitivity, surface lustre, staining, fracture of material, retention, occlusal contour and wear, and colour match of restorations (Success: Scores equal to/above 3)

Secondary Outcome Measures
NameTimeMethod
Survival Rate6 months to 5 years

assessed following FDI criteria on a scale from 1 "very good" to 5 "unacceptable": e.g. post-operative hypersensitivity, surface lustre, staining, fracture of material, retention, occlusal contour and wear, and colour match of restorations (Survival: Score equal to/above 4)

Success Rate6 months to 3 years

assessed following FDI criteria on a scale from 1 "very good" to 5 "unacceptable": e.g. post-operative hypersensitivity, surface lustre, staining, fracture of material, retention, occlusal contour and wear, and colour match of restorations (Success: Scores equal to/above 3)

Quality criteria (Clinical performance)6 months to 5 years

assessed following FDI criteria on a scale from 1 "very good" to 5 "unacceptable": e.g. post-operative hypersensitivity, surface lustre, staining, fracture of material, retention, occlusal contour and wear, and colour match of restorations

Trial Locations

Locations (1)

KU Leuven

🇧🇪

Leuven, Belgium

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