Effects of Proprioceptive Neuromuscular Training on Sensory and Motor Function in Guillain Barre Syndrome

Not Applicable

Completed

• Conditions: Guillain-Barre Syndrome
• Interventions: Other: Proprioceptive Neuromuscular Training; Other: Conventional Physical Therapy

• Registration Number: NCT05491096
• Lead Sponsor: Riphah International University

Brief Summary

This study aims to determine the effects of Proprioceptive Neuromuscular Training on Sensory versus Motor Function in patients presenting with Guillain Barre Syndrome.

Detailed Description

This study will be a randomized controlled trial and will be conducted to determine the effects of proprioceptive neuro-muscular training on sensory and motor function of lower limb,In this study data will be collected from multiple Hospitals of Lahore via Berg Balance Scale, Timed Up and Go test One Leg Stance test before and after intervention. Non- probability convenient sampling technique will be used to enroll 26 patients in total. The patients will be randomly allocated into two groups through lottery method, to either the proprioceptive training group or control group.Both groups will be assessed for proprioception via lower extremity position test as a baseline. Proprioception training programme will be implemented in experimental group and will be carried out for eight weeks, with three (60-minute) sessions per week. It will start with 10 minutes of Warm-up. This will be followed by 30 minutes of proprioceptive exercises targeting lower extremities. Proprioceptive exercises will be divided into three components, standing on Foam with eyes open and eyes closed and passing any object from one subject to the other for 10 minutes, throwing and catching a ball will be performed while standing on foam for additional 10 minutes, throwing and catching a ball, will be performed on trampoline to further challenge the balance system. After each set of 10-minute exercise, the subjects will be given two-minute resting periods. In the end, 10 minutes will be given for cool down exercises to bring the heart rate back to resting level. All participants in both groups will be evaluated before and after the treatment programs. Data will be analyzed by using Statistical Package of Social Sciences Version 26.

Study Timeline

• Study Start: 2022-06-05
• Study First Submitted: 2022-07-14
• Study First Submitted QC: 2022-08-04
• Study First Posted: 2022-08-08
• Primary Completion: 2023-02-28
• Study Completion: 2023-02-28
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-31
• Last Update Posted: 2023-08-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

1. Diagnosed with Guillain Barre Syndrome already taking treatments
2. Inflammatory Demyelinating Guillain Barre Syndrome patients
3. Acute motor sensory axonal neuropathy
4. Guillain Barre Syndrome patients in the subacute phase
5. Guillain Barre Syndrome patients with impaired proprioception
6. Patients with Glasgow Coma Scale above 12

Exclusion Criteria

1. Other Guillain Barre Syndrome types
2. Spinal cord injury
3. Traumatic neuritis
4. Not Fulfilling Above Criteria Of Age

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Proprioceptive Neuromuscular Training	Proprioceptive Neuromuscular Training	It consists of 13 patients who will receive conventional exercises and proprioceptive training with 2 sessions per week for 8 weeks.
Conventional Physical Therapy	Conventional Physical Therapy	It consists of 13 patients who will receive conventional exercises i.e; strengthening exercises, 2 sessions per week for 8 weeks

Primary Outcome Measures

Name	Time	Method
One leg stance test	12th Week	The Single leg Stance Test is used to assess static postural and balance control. Balance assessments are a valuable clinical tool for monitoring neurological and musculoskeletal status as well as for managing fall risk.
Berg Balance Scale	12th Week	The Berg balance scale is used to objectively determine a patient's ability (or inability) to safely balance during a series of predetermined tasks. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of function and takes approximately 20 minutes to completed.
Time up and go test	12th Week	It is used to determine fall risk and measure the progress of balance, sit to stand and walking.It is Simple screening test that is a sensitive and specific measure of probability for falls among older adults.

Trial Locations

Locations (1)

psrd (pakistan Society for the rehabilitation of the disabled); 🇵🇰 Lahore, Punjab, Pakistan