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Clinical Trials/NCT05491096
NCT05491096
Completed
Not Applicable

Comparison of Effects of Proprioceptive Neuromuscular Training on Sensory Versus Motor Function in Patients With Guillain Barre Syndrome

Riphah International University1 site in 1 country26 target enrollmentJune 5, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Guillain-Barre Syndrome
Sponsor
Riphah International University
Enrollment
26
Locations
1
Primary Endpoint
One leg stance test
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This study aims to determine the effects of Proprioceptive Neuromuscular Training on Sensory versus Motor Function in patients presenting with Guillain Barre Syndrome.

Detailed Description

This study will be a randomized controlled trial and will be conducted to determine the effects of proprioceptive neuro-muscular training on sensory and motor function of lower limb,In this study data will be collected from multiple Hospitals of Lahore via Berg Balance Scale, Timed Up and Go test One Leg Stance test before and after intervention. Non- probability convenient sampling technique will be used to enroll 26 patients in total. The patients will be randomly allocated into two groups through lottery method, to either the proprioceptive training group or control group.Both groups will be assessed for proprioception via lower extremity position test as a baseline. Proprioception training programme will be implemented in experimental group and will be carried out for eight weeks, with three (60-minute) sessions per week. It will start with 10 minutes of Warm-up. This will be followed by 30 minutes of proprioceptive exercises targeting lower extremities. Proprioceptive exercises will be divided into three components, standing on Foam with eyes open and eyes closed and passing any object from one subject to the other for 10 minutes, throwing and catching a ball will be performed while standing on foam for additional 10 minutes, throwing and catching a ball, will be performed on trampoline to further challenge the balance system. After each set of 10-minute exercise, the subjects will be given two-minute resting periods. In the end, 10 minutes will be given for cool down exercises to bring the heart rate back to resting level. All participants in both groups will be evaluated before and after the treatment programs. Data will be analyzed by using Statistical Package of Social Sciences Version 26.

Registry
clinicaltrials.gov
Start Date
June 5, 2022
End Date
February 28, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosed with Guillain Barre Syndrome already taking treatments
  • Inflammatory Demyelinating Guillain Barre Syndrome patients
  • Acute motor sensory axonal neuropathy
  • Guillain Barre Syndrome patients in the subacute phase
  • Guillain Barre Syndrome patients with impaired proprioception
  • Patients with Glasgow Coma Scale above 12

Exclusion Criteria

  • Other Guillain Barre Syndrome types
  • Spinal cord injury
  • Traumatic neuritis
  • Not Fulfilling Above Criteria Of Age

Outcomes

Primary Outcomes

One leg stance test

Time Frame: 12th Week

The Single leg Stance Test is used to assess static postural and balance control. Balance assessments are a valuable clinical tool for monitoring neurological and musculoskeletal status as well as for managing fall risk.

Berg Balance Scale

Time Frame: 12th Week

The Berg balance scale is used to objectively determine a patient's ability (or inability) to safely balance during a series of predetermined tasks. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of function and takes approximately 20 minutes to completed.

Time up and go test

Time Frame: 12th Week

It is used to determine fall risk and measure the progress of balance, sit to stand and walking.It is Simple screening test that is a sensitive and specific measure of probability for falls among older adults.

Study Sites (1)

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