CTRI/2020/03/024048招募中不适用
Evaluation of correlation between cervical vertebral maturation, hand-wrist radiographs and salivary alkaline phosphatase levels as indicators for skeletal maturity
Dr LINGANNAGARI SWATHI1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2020年1月5日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Alkaline phosphatase levels in saliva by Calorimetry
研究概览
简要总结
Skeletal maturity assessment plays a key role inorthodontic diagnosis and treatment planning which is commonly done usingradiographic methods like cervical vertebral maturation and hand-wristradiographs, which involves additional radiation exposure.
Newnoninvasive analysis of biological mediators such as insulin-like growthfactor-1 (IGF-1), salivary alkaline phosphatase (ALP), have been investigatedto assess skeletal maturity. Further studies have been recommended toinvestigate the role of these biomarkers in assessing growth status. Hencethe present study is taken up to evaluate if salivary alkaline phosphataselevels can be used toassess skeletal maturity
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 8.00 Year(s) 至 16.00 Year(s)（—）
- 性别
- Female
入选标准
- •Subjects in the age group of 8-16 years females will be selected who require orthodontic therapy Good general health with absence of any nutritional problems.
排除标准
- •Any subject diagnosed with a medical condition systemic disease salivary gland disorders will be excluded Individuals under any medication that could affect bone metabolism during the previous 6 months for example vitamin preparations and calcium supplements.
结局指标
主要结局
Alkaline phosphatase levels in saliva by Calorimetry
时间窗: baseline
次要结局
- cervical vertebral maturation stages from lateral cephalograms(handwrist radiographs)
研究者
研究点 (1)
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