The effectiveness of intermittent screening and treatment (IST) of malaria in pregnancy in South East Nigeria

Not Applicable

• Conditions: Malaria; Pregnancy and Childbirth

• Registration Number: PACTR201308000543272
• Lead Sponsor: niversity of Calabar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-29
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 460

Inclusion Criteria

Pregnancy (16-24 weeks gestation) confirmed at first booking
Willing to have supervised delivery
Permanent residence within the study area

Exclusion Criteria

Haemoglobin < 6.0 g/dl or haematocrit of <18%
Presence of malaria requiring parenteral medication or parasite density ¿ 100,000/mm3 of blood.
Past obstetric and medical history that will adversely affect the evaluation of outcomes.
A prior dose of SP-IPTp
Sensitivity to SP, lumefantrine or an artemisinin
An illness requiring hospital admission.
Known G6PD deficiency to exclude women at risk of haemolytic anaemia.
Women who are known to be HIV infected before enrollment will not be recruited because, according to World Health Organization (WHO) and national recommendations, they should receive 3 (rather than 2) IPTp doses.
Failure to meet any of the inclusion criteria stated above.

Study & Design

• Study Type: Interventional
• Study Design: Not specified