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Triple Recipient Strategy Using Split, Domino, and Auxiliary Techniques

Completed
Conditions
Hepatocellular Carcinoma (HCC)
Registration Number
NCT06683820
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Brief Summary

The investigators report a case of the simultaneous use of split liver transplantation (SLT), domino liver transplantation (DLT) and auxiliary liver transplantation (ALT) to achieve "one donor for three recipients".

Detailed Description

The investigators report a case of the simultaneous use of split liver transplantation (SLT), domino liver transplantation (DLT) and auxiliary liver transplantation (ALT) to achieve "one donor for three recipients". Three recipients had hepatitis C cirrhosis, argininemia, and hepatocellular carcinoma (HCC), respectively. The investigators performed SLT in the first two recipients (an adult and a child), with the donor liver coming from a female who died of severe head trauma. The right lobe of the child, as the "domino liver graft", was transplanted to the postoperative HCC patient, whose left lateral lobe was preserved after tumor resection. All recipients were discharged from the hospital. During the 12 months of follow-up, all three recipients remained alive.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3
Inclusion Criteria
  • liver cirrhosis
  • argininemia
  • hepatocellular carcinoma
Exclusion Criteria
  • Patients who do not require an allogeneic liver transplantation.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postoperative survival time2023/04-2024/04

The duration of time a patient survives after undergoing a surgical procedure.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

2ndAffiliated Hospital, School of Medicine, Zhejiang University

🇨🇳

Hangzhou, Zhejiang, China

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