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Monitoring heparin anticoagulation in major vascular surgery

Completed
Conditions
Haematology and vascular surgery
Surgery
Registration Number
ISRCTN87607734
Lead Sponsor
Royal Free London NHS Foundation Trust (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
40
Inclusion Criteria

All adult patients able to give informed consent and undergoing elective major complex vascular surgery in which heparin anticoagulation and monitoring is indicated

Exclusion Criteria

1. <18 years old
2. Unable to consent
3. History of heparin allergy
4. Already taking part in research study

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Correlate ACT and anti-Xa levels during aortic surgery - measured at baseline and up to six time points during surgery
Secondary Outcome Measures
NameTimeMethod
1. Blood loss and bleeding will be measured during theatre<br>2. Clotting complications will be monitored during theatre and first week postoperatively
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