Determination of the Effectiveness of Oral Chlorine Dioxide in the Treatment of COVID 19
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- negative testing of covid19
研究概览
简要总结
Abstract The objective of this study is to review, through prospective case research, the efficacy of oral chlorine dioxide in the treatment of patients with COVID infection 19. The research will be carried out between April and June 2020 with a quasi-experimental design in two health care centers on a sample of twenty (20) patients, through direct intervention, who will measure the changes in the manifest symptoms of infection and negativity. a COVID 19 after administration of the study preparation, to determine the effectiveness of chlorine dioxide in the treated group.
Based on the results that are found and on the evaluation of efficacy on the basis of clinical improvement on a scale of 1 to 5, and of the negativization of COVID 19, we can conclude whether the therapeutic efficacy in this investigation is considered good by verifying whether or not there is efficacy of treatment with chlorine dioxide in COVID 19.
With this research, it is hoped to stimulate the search for new therapeutic options in the treatment of COVID 19 and contribute to the development of NEW options in medications, considering the immense number of deaths and morbidity that currently exists in the present pandemic.
Key words: COVID 19, chlorine dioxide, treatment.
详细描述
Test plan overview Project phase Phase II
Indication:
Complementary treatment of COVID 19
The purpose of the study:
Examine the efficacy and tolerance of a chlorine dioxide based preparation
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •to. Covid 19 positives b. Some of the characteristic symptoms of covid 19: fever, odynophagia, respiratory distress.
- •c. Age between 18 years and 80 years
- •Criteria Exclusion:
- •to. Covid 19 negatives b. Kidney failure IV / VI. c. Congestive heart failure. d. Patients taking anticoagulants, particularly warfarin sodium
排除标准
- 未提供
研究组 & 干预措施
chlorine dioxide 3000 ppm. Bottle x 150 cc.
Assignment of study medication Each patient will receive, in order of admission to the study, a consecutive patient number and the corresponding study medication. The assignment of this medication was made before the start of the study, using a computer generated list. Patients will receive the 3,000 ppm chlorine dioxide base preparation with written and precise instructions on how to prepare and take the dilutions.
7.1 Dosage and route of administration. Medication: chlorine dioxide 3000 ppm. Fco x 150 cc. 10 ml of 3000 ppm chlorine dioxide are added to 1 liter of water, per day. One part is taken every hour, until the content of the bottle is finished (8 to 12 shots).
Both the original dioxide bottle and the preparation for the day should be kept refrigerated.
干预措施: chlorine dioxide 3000 ppm (Drug)
结局指标
主要结局
negative testing of covid19
时间窗: 7 DAYS
amplification of coronavirus genes by RT-PCR
次要结局
未报告次要终点
研究者
Eduardo Insignares Carrione
research director
Genesis Foundation