Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy

Not Applicable

• Conditions: Knee Osteoarthritis
• Interventions: Drug: Ropivacaine

• Registration Number: NCT02033603
• Lead Sponsor: Changi General Hospital

Brief Summary

Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages. It is a painful surgery and one of the methods to reduce post-operative pain is performing a regional anaesthesia technique. The current practice is to perform a femoral nerve block (FNB) which blocks the nerves supplying the knee joint and the thigh muscles (quadriceps). This provides effective analgesia. However, it also results in weakness of the quadriceps and may result in falls post-operatively.

Adductor canal block (ACB) is a new, alternative regional anaesthesia technique which is hypothesised to provide as effective analgesia, with less quadriceps weakness compared to FNB, hence potentially reducing the risk of falls post-operatively.

Investigators aim to study if the analgesia provided by ACB is as good as FNB while preserving quadriceps strength.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-01
• Study Start: 2014-01
• Study First Submitted: 2014-01-09
• Study First Submitted QC: 2014-01-09
• Study First Posted: 2014-01-13
• Primary Completion: 2014-09
• Study Completion: 2014-12
• Last Update Submitted: 2014-12-31
• Last Update Posted: 2015-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• ages 45-85
• American Society of Anaesthesiologists physical status 1-3
• BMI 18-35 kg/m2

Exclusion Criteria

• inability to give consent, communicate, cooperate
• Patients with regular consumption of strong opioids (morphine, oxycodone) or steroids
• Patients with allergy to local anaesthetics or any drugs included in the study
• Patients with lower limb surgery in the preceding year
• Patients with pre-existing neurological deficits
• Patients who are unsuitable for general anaesthetics (eg difficult airway)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Femoral Nerve Block	Ropivacaine	Femoral Nerve block performed with 0.5% Ropivacaine 30mls (150mg)
Adductor Canal block	Ropivacaine	Adductor Canal block performed with 0.5% Ropivacaine 30mls (150mg)

Primary Outcome Measures

Name	Time	Method
Morphine consumption	first 24 hours

Secondary Outcome Measures

Name	Time	Method
Quadriceps strength, ability to mobilise	24, 48 hours
Side effects of opioids- sedation, nausea and vomiting	48 hours
Morphine consumption	48 hours
Pain scores	1, 6, 12, 24, 48

Trial Locations

Locations (1)

Changi General Hospital; 🇸🇬 Singapore, Singapore