The use of narrow band imaging versus conventional colonoscopy for the detection of dysplasia and cancer in patients with longstanding ulcerative colitis. A randomized cross-over study

Not yet recruiting

• Conditions: inflammatory bowel disease; ulcerative colitis; 10017990

• Registration Number: NL-OMON30287
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 49

Inclusion Criteria

objective diagnosis (endoscopically and histologically proven) of ulcerative colitis
extensive colitis (defined as inflammation proximal to the splenic flexure)
disease history longer than 8 years
inactive disease

Exclusion Criteria

non correctable coagulopathy
age younger than 18 years
inability to give informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The sensitivity of NBI will be compared to WLE in terms of the number of<br /><br>patients with detected neoplasia. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- In addition, the number of detected neoplastic lesions will be compared<br /><br>between both techniques.<br /><br>- Moreover, Kudo*s classification, mucosal morphology and vascular patterns<br /><br>(imaged by NBI) will be evaluated for their ability to distinguish neoplastic<br /><br>and non neoplastic lesions.</p><br>