tility of contrast-enhanced intraoperative ultrasound using Sonazoid in patients undergoing surgery for liver metastasis from colorectal carcinoma - comparison with Gd-EOB-DTPA-MRI, contrast enhanced MDCT, and extracorporeal ultrasound
Not Applicable
- Conditions
- iver metastasis from colorectal carcinoma
- Registration Number
- JPRN-UMIN000005537
- Lead Sponsor
- Cancer institute hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
* History of allergy against Sonazoid or an egg * Contrast-enhanced MDCT or Gd-EOB-DTPA-MRI is impossible based on history of allergy or renal dysfunction * 10 or more liver metastases * Arterio-venous shunt in heart or lung * Severe heart disease * Severe pulmonary disease * Pregnant patients * Nursing mothers * Attending physician or the operator consider the study hazardous
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method *Frequency that contrast-enhanced intraoperative ultrasound alone finds new liver metastases that have not been detected by preoperative imaging studies or intraoperative ultrasound
- Secondary Outcome Measures
Name Time Method *Diagnostic abilities for liver metastasis of contrast-enhanced intraoperative ultrasound, Gd-EOB-DTPA-MRI, contrast-enhanced MDCT, extracorporeal contrast-enhanced ultrasoud and intraoperative ultrasoud *Diagnostic ability of contrast-enhanced intraoperative ultrasound among new focal liver lesions that are found by intraoprative ultrasound *Frequency that the planned surgical precedure is altered through contrast-enhanced intraoperative ultrasound