Enhanced External Counterpulsation (EECP) in Patients with Ischaemic Heart Disease and Chronic Left Ventricular Systolic Dysfunction Evaluatio

Completed

• Conditions: Heart failure; Cardiovascular: Heart failure; Circulatory System

• Registration Number: ISRCTN67553357
• Lead Sponsor: Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Blood and urinary samples will be collected for the purpose of this study. Blood samples will be collected by a medical doctor or specialist nurse according to standard venesection method. 6mls of the blood will be analysed immediately by the local laboratory for NT-BNP, Troponin-T and hs-CRP. The other 8mls will be centrifuged and the plasma will be stored below -20 degree celcius. These will later be analysed using commercially available kits (R & D System, Abingdon, UK) for VEGF, bFGF, HGF, IL-1beta, IL-6 and TNF-a. This will be carried out by experience doctor with support from laboratory technician within the department. 24-hour urinary collection will be analysed in the local laboratory.

1. Over 18 years old
2. Male or female
3. Presence of LVSD with ejection fraction less than 40%
4. Known IHD stable on treatment 3 months prior to randomisation

Exclusion Criteria

1. Patients who have had an ischaemic event within the last 3 months
2. Contraindication to EECP

Study & Design

• Study Type: Interventional
• Study Design: Not specified