Blood pressure changes with different equipment used for anaesthesia

Phase 1

• Conditions: Calculus of gallbladder with othercholecystitis,

• Registration Number: CTRI/2018/04/013537
• Lead Sponsor: Govt Medical College Amritsar

Brief Summary

Hemodynamic changesthat occur during laryngoscopy and intubation can significantly increase therisk of ischemia in cardiac and cerebrovascular patients. Our basic goal willbe directed towards attenuation of these stress responses in ASA grade I and IIpatients. We will divide our patients into three groups A,B and C comprising of30 patients each. Group A will be intubated with conventional Macintoshlaryngoscope, Group B will be intubated with McCoy laryngoscope and Group Cwill be intubated with Video laryngoscope. All these groups will receive samepre-medication and inducing drugs. In the end of the study, hemodynamic changesto different kinds of laryngoscopies will be observed, compared and analysed. Hemodynamicparameters will comprise of heart rate, systolic blood pressure, diastolicblood pressure, mean arterial blood pressure and electrocardiographic changes. TheseHemodynamic parameters will be recorded in patients undergoing intubationduring general anaesthesia in elective open cholecystectomy surgeries.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-30
• Last Update Posted: 2020-01-24

Recruitment & Eligibility

• Status: Other
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• 1.ASA grade I and II patients.
• 2.Patients between 15-65 yrs of age.
• 3.Mallampati grade I and II patients.

Exclusion Criteria

• 1.Patients with hepatic dysfunction, renal dysfunction and severe cardiac dysfunction (ef<55 %) 2.Patients with difficult airway (Mallampati grade III and IV) 3.Morbidly obese patients.
• 4.Patients with neurological disease and severe respiratory disease 5.ASA grade 3 and 4 patients.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the pressor responses during laryngoscopy with macintosh vs McCoy vs video laryngoscope. Pressor responses will be including :-	10 minutes
1. Systolic blood pressure	10 minutes
2. Diastolic blood pressure	10 minutes
3. Mean arterial blood pressure	10 minutes
4.Heart rate	10 minutes
5.Electrocardiographic changes	10 minutes

Secondary Outcome Measures

Name	Time	Method
Any complications arising from above procedure.	2.Any sore throat incidences post extubation.

Trial Locations

Locations (1)

Guru Nanak Dev Hospital Amritsar; 🇮🇳 Amritsar, PUNJAB, India

Guru Nanak Dev Hospital Amritsar

🇮🇳Amritsar, PUNJAB, India

Dr Joginder Pal

Principal investigator

9501025275

drjpattri@gmail.com