The Effect of Phosphorus on Diet Induced Thermogenesis

Not Applicable

Completed

• Conditions: Imbalance of Constituents of Food Intake; Healthy
• Interventions: Dietary Supplement: Phosphorus; Dietary Supplement: Placebo

• Registration Number: NCT02594787
• Lead Sponsor: Lebanese American University

Brief Summary

The aim of the trial is to investigate the effect of ingestion of 75g of glucose (with or without phosphorus) on diet induced thermogenesis (using indirect calorimetry) and appetite (using visual analogue scales) in lean and obese healthy subjects

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03
• Primary Completion: 2014-01
• Study Completion: 2014-01
• Status Verified: 2015-11
• Study First Submitted: 2015-11-01
• Study First Submitted QC: 2015-11-02
• Last Update Submitted: 2015-11-02
• Study First Posted: 2015-11-03
• Last Update Posted: 2015-11-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• Healthy
• Sedentary lifestyle
• Stable weight for the past 3 months
• On a balanced diet

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Exclusion Criteria

• Underweight (BMI<18.5) or overweight/obese (BMI≥25)
• age <18 or > 30 years
• Inability to give valid consent
• Presence of a chronic or acute illness.
• Elevated physical activity level (assesses by the physical activity questionnaire)
• Heavy smokers (≥1 pack per day).
• Weight gain or loss of > 3% in the past 3 months
• History of kidney stones

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Phosphorus	Phosphorus	Intervention (500 mg of potassium phosphate) will be administered with 75 g glucose solution and diet induced thermogenesis will be measured afterwards
Placebo	Placebo	Placebo (cellulose) will be administered with 75 g glucose solution and diet induced thermogenesis will be measured afterwards

Primary Outcome Measures

Name	Time	Method
Diet Induced Thermogenesis	180 minutes (measured every 30 min)	Diet Induced Thermogenesis will be measured using indirect calorimetry (VO2 consumption)