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Kaiser Permanente Evaluating Nutritional Interventions in Food-Insecure High-Risk Adults Study

Phase 3
Recruiting
Conditions
Diabetes Mellitus, Type 2
Interventions
Other: Free home delivery
Other: Financial support for healthy foods and free home delivery
Registration Number
NCT06061861
Lead Sponsor
Kaiser Permanente
Brief Summary

The goal of this randomized controlled trial is to compare the effect of receiving 6 months of monetary support for healthy food through a food delivery platform on change in glycosylated hemoglobin (HbA1c) levels among adults with type 2 diabetes mellitus with glycemic control that is above target level.

The main study aims are to:

1. To evaluate whether providing monthly financial support for home-delivered healthy food vs. only free food delivery through the Instacart platform reduces glycosylated hemoglobin levels within 6 months among Medi-Cal-insured Kaiser Permanente adult members with diabetes mellitus and suboptimal glycemic control.

2. To evaluate whether providing monthly financial support for home-delivered healthy food vs. only free food delivery through the Instacart platform reduces medical resource utilization within 6 months among Medi-Cal-insured Kaiser Permanente adult members with diabetes mellitus and suboptimal glycemic control.

Detailed Description

Eligible Kaiser Permanente adult members will be randomized to one of two groups:

1. Intervention arm, in which subjects will receive 6 months of monetary support (with up to 4 free home deliveries and no service fees) through the Instacart platform to select and receive healthy foods (e.g., vegetables and fruit).

2. Control arm, in which subjects will receive 6 months of free home deliveries and no service fees for up to 4 deliveries each month through the Instacart platform.

Glycosylated hemoglobin level will be assessed at baseline and at 6 months after enrollment. Medical resource utilization will be evaluated at 3 months, 6 months, and 12 months after enrollment. Patient-reported outcomes (i.e., diabetes quality of life, nutrition security, dietary habits, social needs, and food security) will also be assessed at baseline, 6 months, and 12 months after enrollment.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
1100
Inclusion Criteria
  • Adults aged ≥18 years old at enrollment
  • Active membership in Kaiser Permanente with Medi-Cal insurance and no additional private or commercial insurance
  • Diagnosis of Type II diabetes mellitus (not including Type I diabetes mellitus or gestational diabetes mellitus)
  • At least 2 outpatient glycosylated hemoglobin measures ≥7.5% in the prior 18 months
  • Current access to the internet via computer or mobile device
  • No interpreter needed
Exclusion Criteria
  • Advanced or end-stage kidney disease (estimated glomerular filtration rate ≤15 ml/min/1.73m^2 or receiving outpatient dialysis or having a prior kidney transplant)
  • Known pregnancy at time of identification

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Free DeliveryFree home deliveryThe control group will receive only free home delivery through the Instacart platform.
Financial Support and Free DeliveryFinancial support for healthy foods and free home deliveryThe intervention group will receive monthly financial support for healthy food items along with free home delivery through the Instacart platform.
Primary Outcome Measures
NameTimeMethod
6-month change in glycosylated hemoglobin level6 months after enrollment

Baseline glycosylated hemoglobin will be ascertained using routine laboratory tests in the electronic health record prior to enrollment. Participants will complete glycosylated hemoglobin testing 6 months after enrollment.

Secondary Outcome Measures
NameTimeMethod
12-month change in glycosylated hemoglobin level12 months after enrollment

Glycosylated hemoglobin will be ascertained using routine laboratory tests in the electronic health record at 12 months after enrollment.

Change in self-reported level of food security6- and 12-months after enrollment

Participants will answer 10 questions about their food security using the USDA adult food security module. Affirmative responses to questions will be assigned 1 point in the food security scale (out of 10). Participants will be classified as being food secure (0-2 points) or food insecure (3-10 points).

Change in self-reported diabetes-related quality of life6- and 12-months after enrollment

Participants will answer 13 questions about their diabetes-related quality of life, each on a 5-point Likert scale. Scores range from 13-65, with higher scores indicating lower diabetes-related quality of life.

Change in self-reported readiness to change6- and 12-months after enrollment

Participants will be asked about their readiness to change their dietary habits to manage their diabetes on a 5-point Likert scale.

Percentage of participants with glycosylated hemoglobin <7.5%6- and 12-months after enrollment

Baseline glycosylated hemoglobin will be ascertained using routine laboratory tests in the electronic health record prior to enrollment. Participants will complete glycosylated hemoglobin tests 6 months after enrollment. 12-month glycosylated hemoglobin level will be ascertained using routine laboratory tests in the electronic health record.

Change in self-reported level of nutrition security6- and 12-months after enrollment

Participants will be asked about their level of difficulty in accessing healthy food on a 5-point Likert scale. Participants will also be asked 13 questions on reasons for not eating healthy food, with each question scored from 0-2 (Never, Sometimes, Often true). Lower scores indicate higher nutrition security.

All-cause hospitalizations or emergency department visits3-, 6-, and 12-months after enrollment

Occurrence of hospitalization or emergency department visit for any reason within 12 months after enrollment.

Change in self-reported dietary habits6- and 12-months after enrollment

Participants will be asked 8 questions to examine their consumption of fast food, fruits, vegetables, legumes, nuts, dairy, seafood, sweets, and sugar-sweetened beverages over the past month.

Trial Locations

Locations (2)

Kaiser Permanente Southern California Department of Research & Evaluation

🇺🇸

Pasadena, California, United States

Kaiser Permanente Northern California Division of Research

🇺🇸

Pleasanton, California, United States

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