An In Vivo Assessment of the Effects of Using Different Implant Abutment Occluding Materials on Implant Microleakage and the Peri-Implant Microbiome

Stony Brook University1 site in 1 country8 target enrollmentNovember 2013

ConditionsPeri-Implantitis Dental Implant Failed Dental Implant Failure Nos

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Peri-Implantitis
Sponsor: Stony Brook University
Enrollment: 8
Locations: 1
Primary Endpoint: Probing Depth
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The primary purpose of this study is to determine what effect, if any, do different dental materials used to seal the prosthetic screw channels of implant supported restorations have on dental implant health parameters and microbiology.

Registry

clinicaltrials.gov

Start Date

November 2013

End Date

June 2015

Last Updated

10 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Stony Brook University

Responsible Party

Principal Investigator

Julio Carrion

Assistant Professor

Stony Brook University

Eligibility Criteria

Inclusion Criteria

•Fully edentulous patient
•Patient has at least one arch restored with a full-arch dental supported prosthesis

Exclusion Criteria

•poor oral hygiene and motivation (as determined with prosthesis in place)
•uncontrolled diabetes
•pregnant or lactating
•substance abusers
•current smokers
•psychiatric problems or unrealistic expectations
•acute infection in the area intended for implant sealing
•positive to HIV and hepatitis B and C
•affected by autoimmune diseases
•under chronic treatment with steroids or non-steroidal anti-inflammatory drugs.

Outcomes

Primary Outcomes

Probing Depth

Time Frame: 6 months

Secondary Outcomes

Microbial DNA Composition on the Dental Materials Assessed By PCR and Sequencing Protocols(6 Months)
Plaque Index(6 Months)
Gingival Index(6 Months)
Microbial DNA Composition of the Peri-Implant Sulcus Assessed By PCR and Sequencing Protocols(6 Months)