Comparative Effects of Isometric, Concentric, and Eccentric Contraction Exercises on Knee Function in Individuals with Knee Osteoarthritis: A Quasi-Experimental Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- 1. 6-minute walk test
研究概览
简要总结
Background:
Knee Osteoarthritis (OA) is a common degenerative joint disorder that leads to pain, reduced mobility, and impaired functional capacity. Exercise therapy is a cornerstone of non-pharmacological management for OA. However, the differential effects of specific muscle contraction types—isometric, concentric, and eccentric—on knee function remain under-investigated. Understanding the optimal contraction modality could help refine rehabilitation strategies for improved clinical outcomes.
Aim
This study compares the effects of isometric, concentric, and eccentric exercises on knee function in individuals with knee osteoarthritis, focusing on pain, mobility, strength, and quality of life.
OBJECTIVE:
To compare the effects of isometric, concentric, and eccentric quadriceps exercises on pain, mobility, and functional performance in individuals with Knee OA and to identify the most effective contraction modality for improving overall knee function.
Procedure:
Institutional Ethical Committee, SRIHER will be obtained, and the Study will be registered in the Clinical Trial Registry of India. The participants will be screened for eligibility criteria. Once the participant fulfils the inclusion criteria, informed consent will be obtained, and all the baseline assessments will be done for both knee Osteoarthritis individuals. Participants will be allocated into three intervention groups (n=15 per group).
· Isometric Group: Static quadriceps holds
· Concentric Group: Active knee extension exercises
· Eccentric Group: Controlled knee flexion under resistance.
All groups will undergo supervised exercise sessions, 3 times per week for 8 weeks. Baseline and post-intervention measurements will be taken.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 45.00 Year(s) 至 85.00 Year(s)（—）
- 性别
- All
入选标准
- •Individuals clinically diagnosed with unilateral or bilateral Knee OA (Kellgren–Lawrence grade I to II).
- •Age more than 45 years including both men and women.
- •Individuals can walk independently without any assistive devices.
- •NPRS less than 8 score.
排除标准
- •Healthy people.
- •People with walking aids.
- •Individuals who have medical impairments that affect their ability to walk.
- •Participants who are unable to understand or follow instructions due to cognitive impairments or language barriers.
- •Pain Score more than 8 in NPRS.
结局指标
主要结局
1. 6-minute walk test
时间窗: at baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks.
2. Handheld dynamometer
时间窗: at baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks.
3. TUG test
时间窗: at baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks.
次要结局
- NPRS(at baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks)
研究者
Mr YESHWANTH S S
Sri Ramachandra Institute of Higher Education and Research[Deemed to be university]