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临床试验/NCT05487066
NCT05487066已完成不适用

Efficacy of ICU-VTE Scale in Predicting Venous Thromboembolism in ICU Patients

Lijuan Zhang1 个研究点 分布在 1 个国家目标入组 269 人开始时间: 2022年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
269
试验地点
1
主要终点
incidence of VTE

研究概览

简要总结

Venous thromboembolism (VTE) is a common cause of morbidity and mortality among critically ill patients. No uniform standard model of VTE risk for critically ill patients was formatted by now. In 2020, Viarasilpa et al. developed the ICU⁃VTE rating table, mainly for ICU patients. However, it lacks validation. We examined and compared how well the ICU-VTE score predict and stratify VTE risk in comprehensive ICU patients.

详细描述

Venous thromboembolism (VTE) is a group of thromboembolic diseases including deep vein thrombosis (DVT) and pulmonary thromboembolism (PE), which is a systemic disease caused by a combination of risk factors. The risk of venous thromboembolism can be greatly reduced by the preventive treatment of it in hospitalized patients according to their risk level. The common risk assessment tools for inpatient VTE include the Padua score for medical patients and the Caprini score for surgical patients, but there is no clinical basis for implementing risk assessment for critically ill patients. The question of how to perform VTE risk assessment in ICU patients to prevent and treat the occurrence of VTE is worth exploring.

This study was designed according to a prospective study method. Data and information were collected from the time the patients were admitted to the ICU to the time the patients were discharged from the ICU.There are three purposes for this study. First, to observe the predictive effect and evaluate the value of the ICU-VTE scoring scale in comprehensive ICU patients; Second, to compare the advantages and disadvantages of the ICU-VTE scoring tool with the Padua score (internal medicine) and Caprini score tool (surgery); To analyze the risk factors for VTE in comprehensive ICU patients and to optimize the VTE risk prediction model; Third, to look into the prevention and treatment of VTE in critically ill ICU patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients age greater than or equal to 18 years;
  • Patients or their family members agreed to the study and signed informed consent.

排除标准

  • Patients admitted to ICU with VTE diagnosis or diagnosed with VTE within 24 hours of admission to ICU;
  • Use the therapeutic dose of anticoagulation before admission to ICU or within 24 hours in ICU;
  • Expected ICU stay of less than 48 hours;
  • Patients cannot obtain imaging data to confirm the presence of VTE during ICU admission

结局指标

主要结局

incidence of VTE

时间窗: 28-day

inhospital venous thromboembolism occurrence

次要结局

  • all-cause mortality(28-day)

研究者

发起方
Lijuan Zhang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Lijuan Zhang

physician

Wuhan Central Hospital

研究点 (1)

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