Study to compare changes in blood glucose levels in patients undergoing infraumbilical surgeries under spinal versus general anaesthesia

After obtaining ethical committee clearance, patients aged 18-60 years belonging to ASA class I and II undergoing elective infraumbilical surgeries under either spinal anaesthesia or general anaesthesia fulfilling the pre determined inclusion and exclusion  criteria will be enrolled in the study. The data shall be recorded using a semi structured proforma which contains 2 parts.

1.     The first part contains the details regarding socio-demographic characteristics like name, age, sex and baseline values of Pulse rate, Systolic and Diastolic  Blood pressure, Mean Arterial Pressure and SpO2 will be recorded.

2.     The second part contains the details of time of induction of spinal anaesthesia/general anaesthesia and the capillary blood glucose levels just before induction.

GA group: Patients undergoing infraumbilical surgeries under general anaesthesia as follows: pre-oxygenation with 100% oxygen, induction with 2mg/kg of propofol, 2mcg/kg of Fentanyl, and 2mg/kg vecuronium for tracheal intubation, maintaining anaesthesia with oxygen, nitrous oxide, sevoflurane, and vecuronium. At the end of the surgery, patients will be reversed with glycopyrolate and neostigmine followed by tracheal extubation.

SA group: Patients undergoing infraumbilical surgeries under spinal anaesthesia receiving 0.5% heavy bupivacaine 15mg in L3-L4 interspace using 25G Quincke’s needle and in whom sensory block was achieved to T6 dermatomal level.

Patients will be administered with adequate intravenous crystalloid fluids like normal saline as a part of routine intraoperative management.

Capillary blood glucose levels (CBG) will be noted four times through out the perioperative period.

Time 1 (T1): preoperatively 5 mins before induction of anaesthesia as a baseline value

Time 2 (T2): intraoperatively 30 mins after induction of anaesthesia.

Time 3 (T3): immediately at the end of surgery in both the groups.

Time 4 (T4): postoperatively 60 mins after the end of surgery in the recovery room. During each time sample taking, the tips of fingers of the non dominant hand were disinfected with an alcohol swab before pricking with a lancet to measure capillary blood glucose levels