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Deflazacort Expanded Access Program for Children, Adolescents and Adults With Duchenne Muscular Dystrophy

Conditions
Duchenne Muscular Dystrophy
Registration Number
NCT02592941
Lead Sponsor
PTC Therapeutics
Brief Summary

The expanded access program will provide access to treatment with deflazacort in children, adolescent, and adult patients with DMD in the U.S. who are ineligible, unable, or otherwise unwilling to enroll in a clinical study examining the efficacy of deflazacort while a new drug application is under preparation and review. Enrollment is open to all eligible patients.

Detailed Description

Deflazacort will be supplied free of charge and shipped directly to patients or caregivers, as appropriate. Treating physicians will continue to follow their standard of care activities and procedures for management of DMD. Treating physicians participating in the expanded access program are required to collect/document any patient or caregiver reported safety events and report to the sponsor..

Recruitment & Eligibility

Status
APPROVED_FOR_MARKETING
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Confirmed diagnosis of Duchenne muscular dystrophy
  • The patient is ≥ 5 years old
  • Current on all childhood vaccinations including the chicken pox vaccine

Main

Exclusion Criteria
  • History or current medication condition that could affect safety or poses an additional risk
  • Hypersensitivity or allergic reaction to steroids or their formulations

Study & Design

Study Type
EXPANDED_ACCESS
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (42)

Phoenix Children's Hospital

🇺🇸

Phoenix, Arizona, United States

Arkansas Children's Hospital

🇺🇸

Little Rock, Arkansas, United States

UCLA Health

🇺🇸

Los Angeles, California, United States

Childrens Hospital of Orange County

🇺🇸

Orange, California, United States

UC Davis Medical Center

🇺🇸

Sacramento, California, United States

Children's Hospital Colorado

🇺🇸

Aurora, Colorado, United States

Children's National Medical Center

🇺🇸

Washington, District of Columbia, United States

University of Florida Clinical Research Center

🇺🇸

Gainesville, Florida, United States

Nicklaus Children's Hospital

🇺🇸

Miami, Florida, United States

Shriner's Hospital for Children - Tampa

🇺🇸

Tampa, Florida, United States

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Phoenix Children's Hospital
🇺🇸Phoenix, Arizona, United States
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