Comparison of effects of mixed versus sequential adminstration of levobupivacaine and fentanyl in spinal anaesthesia for leg surgeries.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: T07- Unspecified multiple injuries
- Registration Number
- CTRI/2021/08/035540
- Lead Sponsor
- Sharda hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of age between 18-65 years.
American Society of Anaesthesiologists (ASA) grade I&II
Scheduled for lower limb surgeries under subarachnoid block
Exclusion Criteria
1)Patient refusal to participate in the study
2)Any History of allergy to the study medication
3)Any history of clotting or bleeding disorder
4)Infection at the site of lumbar puncture
5)Patients with pre existing neurological deficit
6)Any history of psychiatric illness
Pregnant patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To compare subarachnoid block characteristics after mixed versus sequential administration of levobupivacaine and fentanyl for lower limb surgeries. <br/ ><br>2.To compare intraoperative hemodynamic parameters between the three groups. <br/ ><br>Timepoint: 1)Sensory block was assessed by a sterile pin prick every 2 min till 20 min and then after every 10 min till the highest level was achieved. <br/ ><br>2)Onset was defined as the loss of sensation at T10 dermatome. The time to onset of motor block was defined as time taken to reach Modified Bromage score of 4. <br/ ><br>3)Time of regression of motor block was assessed as time to reduce to from maximum attained Modified Bromage score to score of 0.
- Secondary Outcome Measures
Name Time Method 1.To compare the duration of postoperative analgesia between the three groups. <br/ ><br>2.To evaluate opioid related side effects in the three groups. <br/ ><br>Timepoint: Analgesia remaining in the postoperative period will be assessed by VAS scale at hourly intervals for eight hours after completion of surgery