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临床试验/CTRI/2018/03/012400
CTRI/2018/03/012400已完成1 期

Clinical Evaluation of Harijiwan Oil in the treatment of Sandhivata (Osteoarthritis)

Harijiwan Pharmacy1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2017年1月6日最近更新:

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
Reduction in joint pain related to O.A. and free movement of the joints.

研究概览

简要总结

The investigators are quite sure on the efficacy of Harijiwan Oil, a polyherbal oil containing garlic, clove, karpura, castor oil, black peeper, ajwain, nutmeg , pippali, cinnamomum, nilgiri oil sunthi and Dash mool in varied proportion; in the management of O.A. basing on the outcomes of the present study .The trial drug was found effective in improving all the signs and symptoms of OA. The mean scores of pain was reduced from 2.89 to 0.89, swelling reduced from 2.74 to 0.84, stiffness reduced from 2.70 to 0.74, crepitation reduced from 2.63 to 0.79, pain during extension and flexion reduced from 2.82 to 0.89, and tenderness reduced from 2.69 to 0.96. The mean overall score reduced from 15.61 to 4.86. All the above mentioned changes were found extremely significant statistically with p<0.0001. The overall rating of the product , we got good results in 78.87% cases, Excellent result in 14.29% cases and moderate result in 7.14% cases. Therefore only mild cases of O.A. should be prescribed for oil message, but moderate and severe to chronic cases should be prescribed with oral anti-arthritic drugs for better results.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
30.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • All patients presenting with the clinical features of Osteoarthritis
  • Patients diagnosed to be suffering from osteoarthritis
  • Patients of Osteoarthritis who have gone for any type of treatment with or no sub optimal relief.

排除标准

  • Severe and complicated case of Osteoarthritis
  • Patient not complying the Direction of the Physician.
  • Any condition which can not be rendered as a case of O.A.

结局指标

主要结局

Reduction in joint pain related to O.A. and free movement of the joints.

时间窗: 24 weeks

次要结局

  • Reduction in swelling of the joints(14 weeks)

研究者

发起方
Harijiwan Pharmacy
申办方类型
Pharmaceutical industry-Indian

研究点 (1)

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