JPRN-jRCTs051180050已完成未知
The investigation for the beneficial effect of improvement of postprandial hyperglycemia on frailty or sarcopenia
Akasaka Hiroshi0 个研究点目标入组 5 人开始时间: 2019年2月7日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 5
研究概览
简要总结
We examined the effect of a combination of glinide and alpha-glucosidase inhibitor on muscle mass and function in older diabetic patients with frailty and postprandial hyperglycemia. However, we cannot conclude from this study because we did not achieve the target number of cases. We decided to terminate this study because we cannot complete the target number due to the transfer of the head of this research, the pandemic of COVID-19, and the other studies targeting similar participants.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 65age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1) the subjects aged 65 years or older with type 2 diabetes treated with DPP-4 inhibitors or GLP-1 analogs
- •2) the subjects diagnosed as 'pre-frailty' by CHS classification of frailty
- •3) the subjects treated without or can stop treatment with the drugs as follows: sulfonylureas, glinides, alpha-glucosidases, and rapid-acting insulins
- •4) the subjects with 200mg/dl or over of adlib blood glucose level (>twice a week)
- •5) the subjects that an agreement was provided in a document
排除标准
- •1) the subjects with type 1 diabetes
- •2) the subjects with HbA1c less than 7.5%
- •3) the subjects with uncontrolled hypertension (SBP >= 160mmHg)
- •4) the subjects with effort angina, chronic heart failure, and tachyarrhythmia
- •5) the subjects with chronic respiratory failure
- •6) the subjects not able to walk by themselves
- •7) the subjects with chronic kidney disease
- •8) the subjects with severe hepatic dysfunction
- •9) the subjects not preserved basic ADL and instrumental ADL
- •10) the subjects with cognitive impairment
- •11) the subjects with gastrointestinal surgery
- •12) the subjects participating other clinical investigations
- •13) the subjects who are judged by the investigators to be not suitable for participation in the study
研究者
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