Effect of Meal on Portal and Esophagus Variceal Pressure

Not Applicable

Terminated

• Conditions: Cirrhosis; Esophageal Varices

• Registration Number: NCT00485290
• Lead Sponsor: Hvidovre University Hospital

Brief Summary

The reason why esophagus varices suddenly rupture and start to bleed is unclear. Food intake increase the hepatic blood flow and the portal pressure, but it is yet unknown if there is also an increase in variceal pressure. The aim of this study is to evaluate the efficacy of a meal on variceal pressure with a non invasive endoscopic measurement device, and compare it with portal pressure.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-06
• Study First Submitted: 2007-06-11
• Study First Submitted QC: 2007-06-11
• Study First Posted: 2007-06-12
• Status Verified: 2007-11
• Primary Completion: 2008-04
• Study Completion: 2008-04
• Last Update Submitted: 2008-08-06
• Last Update Posted: 2008-08-07

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Large Esophageal varices

Exclusion Criteria

• Treatment with beta-blocking agents
• Respiratory diseases that contradict endoscopy
• Gastric-retention
• Former gastric resection
• Resent sclerotherapy or former banding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
effect of meal on variceal pressure	30 minutes after the meal

Trial Locations

Locations (1)

Hvidovre Hospital; 🇩🇰 Hvidovre, Denmark