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A prospective randomized study of corticosteroid withdrawal in low-risk kidney transplant recipient selected by immune monitoring method

Not Applicable
Terminated
Conditions
Not Applicable
Registration Number
KCT0000664
Lead Sponsor
Samsung Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Terminated
Sex
All
Target Recruitment
236
Inclusion Criteria

1.Primary live donor transplant patients aged 18 to 65 years
2.Either female patients of child bearing potential with negative pregnancy test and agreed to practice birth control while receiving or male patients
3.Patients must be willing and able to provide written informed consent.

Exclusion Criteria

1.Deceased donor transplant patients
2.Patients who have HLA identical live donor
3.Patients who have current PRA > 50%.
4.Patients who are recipients of or schedulled for non-renal transplants.
5.Patients with known positive results of the following serological tests: HIV-1 Ab, HbsAg, or anti-HCV ab.
6.Patients with evidence of active infection.
7.Patients with a history of malignancies.
8.Patients who have congestive heart failure (Ejection fraction < 35%)

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Biopsy-proven acute rejection
Secondary Outcome Measures
NameTimeMethod
Patient survival;Graft survival
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