Metabolic effects of morning light in obesity and type 2 diabetes - SUNRISE 2

Academisch Medisch Centrum0 个研究点目标入组 16 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Group 1 (n<=8):
•- age 18-80 years
•- male sex
•- BMI >25 kg/m2
•- habitual wake-up time between 6:00 and 9:00
•- no DM2: fasting venous plasma glucose <6.1 mmol/l and HbA1c <6.5%;Group 2 (n<=8):
•- age 18-80 years
•- male sex
•- BMI >25 kg/m2
•- habitual wake-up time between 6:00 and 9:00
•- type 2 diabetes: fasting venous plasma glucose >6.9 mmol/l or HbA1c > 6.5%

•- use of any other medication than metformin that interferers with glucose metabolism or neuronal synaptic transmission (corticosteroids, anti-depressants, anti-epileptic medication, other psychotropic drugs, anti malarials)
•- gastro-intestinal or metabolic disease that will interfere with digestion or metabolism
•- neuropsychiatric illness including severe depression
•- epilepsy
•- hypertension
•- ophthalmological abnormalities (e.g. retinopathy)
•- lactose intolerance
•- soy allergy

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