Role of intraaortic Adenosine in Postconditioning during CABG Surgery
Not Applicable
- Conditions
- Surgery
- Registration Number
- PACTR201604001601522
- Lead Sponsor
- Minoufiya University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients undergoing elective CABG aged 40-70 y.with 2-4 Vessel disease
EF in the range of 25-50%.
Exclusion Criteria
age > 75 years, recent myocardial infarction, moderate to severe valvular lesions, hypertrophic obstructive cardiomyopathy (HOCM), pulmonary hypertension(mean pulmonary pressure >35mmhg), pericardial disease and infiltrative myocardial disease, patients with implantable pacemaker, emergency CABG, patients coming on inotropes, vasodilators or mechanical ventilation, significant pulmonary, hepatic or renal disease and oesophageal pathology.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The cardiac troponin I (cTnI) and creatine kinase isoenzyme MB (CK-MB), ;Ejection fraction (EF),fractional shortening(FS),Also we will assess signs of wall motion abnormalities(WMA). and cardiac index(CI) which will be measured by TEE.Also we will assess signs of wall motion abnormalities(WMA). ;Diastolic function indices will be tested by (trans-mitral diastolic doppler flow profile) and tissue doppler imaging (TDI)
- Secondary Outcome Measures
Name Time Method