Investigation of the Efficacies of a Resveratrol Formula on Improvement of Skin Conditions and Inflammatory Related Factors
- Conditions
- Skin ConditionsProinflammatory Cytokines
- Registration Number
- NCT04456829
- Lead Sponsor
- TCI Co., Ltd.
- Brief Summary
To assess a resveratrol formula on improvement of skin conditions and inflammatory cytokines in blood
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Healthy volunteers aged above 20 years old
- Subject who is not willing to participate in this study.
- Patients with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history).
- Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
- Subjects who have large spots (area >3 square centimeter) or abnormal acne.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method The change of IL-17 of blood 0 and 8 weeks ELISA Kit
The change of skin collagen density 0, 4, and 8 weeks DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units:
Intensity scoreThe change of TNF-alpha of blood 0 and 8 weeks ELISA Kit
The change of skin moisture 0, 4, and 8 weeks Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin elasticity 0, 4, and 8 weeks Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves
The change of skin wrinkles 0, 4, and 8 weeks VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units
The change of skin texture 0, 4, and 8 weeks VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of total antioxidant capacity of blood 0 and 8 weeks Total Antioxidant Capacity Assay Kit
The change of skin pores 0, 4, and 8 weeks VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units
The change of IL-6 of blood 0 and 8 weeks ELISA Kit
The change of IL-1β of blood 0 and 8 weeks ELISA Kit
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chia Nan University of Pharmacy & Science
🇨🇳Tainan City, Taiwan
Chia Nan University of Pharmacy & Science🇨🇳Tainan City, Taiwan