Post-Myocardial Infarction Patients in Santa Catarina, Brazil: a Prospective Cohort Study - Catarina Heart Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 1,426
- 试验地点
- 1
- 主要终点
- MACE in 1 year
研究概览
简要总结
Prospective cohort evaluating patients in the State of Santa Catarina (Brazil) with the diagnosis of the first acute myocardial infarction from July 2016 until December 2020.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 18 years;
- •Presence of precordial pain suggestive of acute myocardial infarction associated with electrocardiogram with new ST segment elevation in two contiguous leads with limits: ≥0.1 mv in all leads other than leads V2-V3 where the following limits apply : ≥0.2 mv in Men ≥40 years; ≥0.25 mV in men <40 years, or ≥ 0.15 mV in women or presence of precordial pain suggestive of acute myocardial infarction associated with elevation of troponin I or CK-MB above the 99th percentile of the upper reference limit
排除标准
- •Previous acute myocardial infarction;
- •Disagreement with the Terms of Informed Consent.
结局指标
主要结局
MACE in 1 year
时间窗: Major cardiovascular events - MACE (cardiovascular death, nonfatal infarction, unstable angina or stroke) in 1 year
MACE in 30 days
时间窗: Major cardiovascular events - MACE (cardiovascular death, nonfatal infarction, unstable angina or stroke) in 30 days
Restenosis in 30 days
时间窗: Restenosis incidence in 30 days
Death in 1 year
时间窗: Death incidence in 1 year
Death in 30 days
时间窗: Death incidence in 30 days
Restenosis in 1 year
时间窗: Restenosis incidence in 1 year
Intrastent thrombosis in 1 year
时间窗: Intrastent thrombosis incidence in 30 days
Intrastent thrombosis in 30 days
时间窗: Intrastent thrombosis incidence in 30 days
Cardiovascular death in 1 year
时间窗: Cardiovascular death incidence in 1 year
Cardiovascular death in 30 days
时间窗: Cardiovascular death incidence in 30 days
Nonfatal infarction in 1 year
时间窗: Nonfatal infarction incidence in 1 year
Nonfatal infarction in 30 days
时间窗: Nonfatal infarction incidence in 30 days
Stroke in 1 year
时间窗: Stroke incidence in 1 year
Unstable angina in 1 year
时间窗: Unstable angina incidence in 1 year
Unstable angina in 30 days
时间窗: Unstable angina incidence in 30 days
Stroke in 30 days
时间窗: Stroke incidence in 30 days
次要结局
- Creatinine(Creatinine in 72 hours)
- Troponin levels(Troponin levels in 72 hours)
- Epidemiological profile(Epidemiological profile of hospitalized patients with infarction in Santa Catarina at the admission)
- Fish consumption(Fish consumption at admission)
- Red meat consumption(Red meat consumption at admission)
- Red Cell Distribution Width (RDW)(Red Cell Distribution Width (RDW) in 72 hours)
- Chocolate consumption(Chocolate consumption at admission)
- Caffeine consumption(Caffeine consumption at admission)
- Cognitive level(Cognitive level at admission)
- Religiosity(Religiosity at admission)
- Pre-infarct physical activity(Pre-infarct physical activity at admission)
- Ventricular function post-infarction(Ventricular function post-infarction (evaluated within 72 hours of admission))
- Alcoholic beverages consumption(Alcoholic beverages consumption at admission)
- Illegal drugs consumption(Illegal drugs consumption at admission)
- Depression(Depression at admission)
- Syntax score(Syntax score at admission)
- TIMI frame count(TIMI frame count in patients with primary angioplasty at admission)
- Hospitalization in 1 year(Hospitalization incidence in 1 year)
- Hospitalization in 30 days(Hospitalization incidence in 30 days)
- Bleeding in 1 year(Bleeding incidence in 1 year)
- Bleeding in 30 days(Bleeding incidence in 30 days)
- Hematocrit and hemoglobin(Hematocrit and hemoglobin at the admission)
- Leukocytes(Leukocytes in 72 hours)
- Hematocrit and hemoglobin in 72 hours(Hematocrit and hemoglobin in 72 hours)
- CHA2DS2-VASc Score(CHA2DS2-VASc Score at admission)
- Cholesterol levels(Cholesterol levels in 72 hours)
- C-reactive protein(C-reactive protein in 72 hours)
研究者
Daniel Medeiros Moreira
Clinical vice-director
Instituto de Cardiologia de Santa Catarina