Single procedure brachytherapy in cervical cancer
- Conditions
- Health Condition 1: null- Cancer of Uterine Cervix
- Registration Number
- CTRI/2017/03/008172
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
1) Histologically diagnosed invasive cervical cancer (squamous carcinoma, adenosquamous carcinoma, adenocarcinoma)
2) FIGO stage II B - IV A after thorough clinical examination and work-up investigation.
3) Suitable for radical radiation therapy with/without chemotherapy, and also for brachytherapy boost.
4)Accepts the Informed consent process and signs the form on his/her will.
1)Patients with vesico-vaginal fistula or recto-vaginal fistula at diagnosis.
2)Patients at high risk of anaesthesia and patients with phobia /contra-indications to undergo MRI.
3)Patients not suitable for brachytherapy.
4)Metastatic disease beyond iliac on standard imaging.
5)Vault cancers/recurrence.
6)Previous history of pelvic radiation.
7)Non-compliance to treatment.
8)Medical or psychological illness precluding treatment protocol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)To evaluate feasibility to achieve dosimetric constraints for target and organs at risk, thus safety to deliver multi-fractionated brachytherapy in a single applicationTimepoint: 1 year
- Secondary Outcome Measures
Name Time Method 1)To evaluate inter fraction dose variation for organs at risk <br/ ><br>Timepoint: 1 year;To assess clinical outcomes in terms of late Gastrointestinal (GI)/Genitourinary (GU)/vaginal toxicities (grade 3 or more) and local control rates. <br/ ><br>Timepoint: 2 years