Efficacy of Sublingual administration Misoprostol 600 mcg versus 800 mcg for induced abortion in women with early pregnancy loss: A Randomized Controlled Trial

Phase 4

Completed

• Conditions: Pregnant women which gestational age less than 12 weeks with early pregnancy loss.; Early pregnancy loss; Medical abortion; Misoprostol

• Registration Number: TCTR20210303009
• Lead Sponsor: o

Brief Summary

There was no significant difference in success rate between 2 groups, however, the 800 mcg misoprostol was higher rate of success and side effects were not different to 600 mcg group

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-01-31
• Study Start: 2021-03-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 105

Inclusion Criteria

18-year-old pregnant women who were below 12 weeks of gestational age and diagnosed with an early pregnancy loss with stable vital signs, closed internal cervical os, no contraindication for misoprostol, no active bleeding, no abnormal pregnancy (ectopic pregnancy, molar pregnancy) were included

Exclusion Criteria

Women who were not able to follow up were excluded from this study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
success rate within 7 days Transvaginal ultrasound after 7 days of administration of misoprostol

Secondary Outcome Measures

Name	Time	Method
success rate within 7 days within 7 days after administration misoprostol, if ET less than 10mm defined as complete abortion which is success rate