Success rate evaluation of Infertility procedure

Phase 4

Completed

• Conditions: Health Condition 1: null- Luteal Phase Deficiency

• Registration Number: CTRI/2014/02/004407
• Lead Sponsor: Sooriya Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

• Married females (18 to 33 yrs) with at least Three years history of Infertility

• Suspected or documented evidence of Luteal Phase defect with or without history of Recurrent pregnancy loss, OR

• Unexplained infertility

Exclusion Criteria

• History of Progesterone (Natural or synthetic) use in the past three months

• History of tubal insufficiency or obstruction including Endometriosis or Polycystic Ovarian Syndrome

• History of psychoactive disease or on antidepressants

• AST and / or ALT more than 2.5 x ULN (active liver disease)

• Serum creatinine more than 1.5 mg/dl (active renal disease)

• Women with Uncontrolled hypertension, hypercholesterolemia or diabetes

• Women with history of smoking, myocardial infarction, stroke, cardiovascular/circulatory or clotting disorders

• Women on oral anticoagulants or prolonged use of high doses of NSAIDs

• Hypersensitivity to Natural micronized progesterone or Dydrogesterone

Study & Design

• Study Type: PMS
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage patients with successful pregnancy confirmed by Urinary HCGTimepoint: 4 weeks

Secondary Outcome Measures

Name	Time	Method
Percentage patients with Sr. Progesterone levels more than 10 ng/mlTimepoint: Day 23 of the cycle