Mid point transverse process to pleura block versus thoracic paravertebral block for post operative analgesia in patients undergoing Modified radical mastectomy-a randomized controlled non inferiority study (Academic trial)
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- To compare post operative pain scores
研究概览
简要总结
Most patients undergoing breast surgery complain of acute postoperative pain in the chest, arm, and axilla. If untreated, this leads to chronic pain and restriction of shoulder movements, thus decreasing the quality of life of breast cancer survivors. Preventive analgesia through multimodal approaches ensures control of continuous neuronal firing, which eventually decreases the incidence of chronic pain, morbidity, and mortality. Among the various regional anesthesia techniques used for postoperative analgesia in the) modified radical mastectomy (MRM), thoracic paravertebral block (TPVB) is presently considered the technique of choice. Recently, a newer technique, “midpoint transverse process to pleura” (MTP) block has been described in which the tip of the needle is placed at the midpoint between the transverse process and pleura. MTP block is a novel technique that has been hypothesized to be a safe alternative that achieves paravertebral block with an injection between the midpoint of the posterior transverse process and pleura.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients undergoing modified radical mastectomy.
排除标准
- •Patient refusal, Patient’s age less than 18years of age and greater than 65 years of age, ASA PS 3 and above, Patients with known allergy to local anaesthetics, Infection at the site of needle puncture, Bleeding diathesis, Presence of tumour in the paravertebral region and thoracic spine deformity.
结局指标
主要结局
To compare post operative pain scores
时间窗: Patients will be assessed immediately after shifting to post operative room followed by 4th hourly till 12 hours and 12th hourly till 48 hours
次要结局
- To measure post operative consumption of other analgesics, to assess the complications involved in both techniques, to measure the duration of both blocks, to assess hemodynamic changes post operatively(Patients will be assessed immediately after shifting to post operative room followed by 4th hourly till 12 hours and 12th hourly till 48 hours)
研究者
Damu Harish Kumar
AIIMS MANGALAGIRI
