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Clinical Trials/NCT06138197
NCT06138197
Completed
Not Applicable

Comparative Evaluation of Three Surgical Robotic Platforms for the Laparoscopic Hysterectomy Procedure: Post Market Clinical Follow Up Study

Universita di Verona1 site in 1 country150 target enrollmentStarted: January 4, 2024Last updated:
ConditionsHysterectomy

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Universita di Verona
Enrollment
150
Locations
1
Primary Endpoint
Textbook outcome satisfaction

Overview

Brief Summary

Hysterectomy is the most common procedure in gynaecology after a cesarean section. In recent years, the laparoscopic approach has become preferred given the different advantages over the traditional laparotomic approach, and both conventional laparoscopy and robotic-assisted laparoscopy have become the standard approach for hysterectomy. To date, robotic-assisted laparoscopic hysterectomy has been performed using one robotic platform and only recently, two new robotic platforms have been introduced in clinical practice. Although all three are registered for human use and available for clinical practice, there are currently not enough clinical experiences and data in the literature to evaluate the efficacy, safety and relationship between cost and efficacy of the new platforms available for the robotic-assisted laparoscopic hysterectomy. For this reason, the investigators will conduct an exploratory clinical study on a Post Market Clinical Follow up (PMCF) medical device aimed at performing a preliminary assessment of the global performance of the ITL procedure implemented using the three robotic platforms currently available.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients undergoing elective total laparoscopic hysterectomy surgery
  • Age \> 18 years
  • Signature of the informed consent

Exclusion Criteria

  • Patients undergoing emergency surgery
  • Patients who are candidates for hysterectomy for a non-gynaecological indication
  • Patients undergoing previous radiation therapy
  • Patients unable to express adequate informed consent to participate in the study

Outcomes

Primary Outcomes

Textbook outcome satisfaction

Time Frame: 90 days after surgery

Robotic-assisted hysterectomy performed without laparotomy conversion, intraoperative complications, postoperative complications (Clavien-Dindo classification ≥2), the performance of postoperative imaging excluding transvaginal ultrasound, reoperation, length of stay after day of surgery \>2 days, readmission within 90 days, mortality, surgery length greater than 120 minutes, or intraoperative blood loss greater than 100mL. The Textbook outcome will be considered fulfilled if all conditions are met.

Secondary Outcomes

  • Operative time(During surgery)
  • Intraoperative complications(During surgery)
  • Intraoperative blood loss(During surgery)
  • Postoperative complications(30 and 90 days after surgery)
  • Sexual function(90 and 180 days after surgery)

Investigators

Sponsor
Universita di Verona
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Stefano Uccella

Clinical Professor

Universita di Verona

Study Sites (1)

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