Randomiazed controlled trial comparing docetaxel-cisplatin combination with docetaxel alone in elderly patients with advanced non-small-cell lung cancer(JCOG0803/WJOG4307L)

Phase 3

• Conditions: non-small-cell lung cancer

• Registration Number: JPRN-UMIN000001424
• Lead Sponsor: Japan Clinical Oncology Group(JCOG)

Brief Summary

See the datails via "URL releasing results" above. Also the details can be seen in the JCOG website: http://www.jcog.jp/en/trials/index.html

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-10-10
• Study Completion: 2011-09-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 380

Inclusion Criteria

Not provided

Exclusion Criteria

1) Symptomatic brain metastasis 2) Active another neoplams 3) Severe SVC syndrome 4) Massive pericardial, pleural effusion, or ascites 5) Bone metastasis emergent for palliative radiotherapy or surgery 6) Uncontrollable systemic hypertension 7) Heart failure, Unstable angina, Myocardial infarction within 6 months 8) Uncontrollable diabetes 9) Active infection other than viral hepatitis 10) Hepatitis B virus infection 11) Interstitial pneumonia/ Pulmonary fibrosis 12) Hypersensitivity for polysolbate 80 13) Systemic administartion of corticosteroids

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
overall survival

Secondary Outcome Measures

Name	Time	Method
adverse events, progression-free survival, response rate, complete response rate, Symptom Score