Effects of Repetitive Transcranial Magnetic Stimulation on Heart Rate Variability

University of Sao Paulo1 site in 1 country30 target enrollmentApril 1, 2018

ConditionsHeart Rate Variability

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Heart Rate Variability
Sponsor: University of Sao Paulo
Enrollment: 30
Locations: 1
Primary Endpoint: Heart rate variability changes
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Repetitive transcranial magnetic stimulation is a non-invasive neuromodulation technique used to treat different neuropsychiatric disorders, such as, depression, neuropathic pain, fibromyalgia and obsessive-compulsive disorder. It is known that the heart rate variability is altered in these conditions. Therefore the focus of this research is to show the influence of rTMS on the Heart Rate Variability.

Registry

clinicaltrials.gov

Start Date

April 1, 2018

End Date

December 2018

Last Updated

7 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

University of Sao Paulo

Responsible Party

Principal Investigator

Ricardo Galhardoni

assistant professor, Clinical Research

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

•Agreed participate the protocol
•Signing the consent form
•Do not present any cardiac problems or disease

Exclusion Criteria

•Trauma of Skull, epilepsy don't treated,
•Use of medications decrease the seizure threshold
•Patients in use of drugs, how cocaine and alcohol
•Neurosurgical clips, pacemakers, increased intracranial pressure (risk of sequelae after seizure)
•Pregnant or breastfeeding women

Outcomes

Primary Outcomes

Heart rate variability changes

Time Frame: Three times during the entire study. Following the scheme, Until 1 hour before each session, 15 minutes along the each session and until 1 hour after the end of session

Changes in heart rate variability measured by Polar V800