The effect of dual strain probiotic on the growth and feeding intolerance in premature neonates of Kabul city: A randomized clinical trial

Professor Mansoor Aslamzai, MD0 个研究点目标入组 107 人开始时间: 2020年5月1日最近更新: 2021年9月20日

适应症

试验速览

Research question: Does dual strain probiotics increase the weight gaining and feeding intolerance of preterm neonates? 2. Background information: Prematurity is prevalent worldwide and accounts for the leading cause of neonatal death. Slow weight gain, feeding intolerance, prolong hospital stay, and high mortality are significant issues for preterm neonates. Dual strain probiotics can manage such complications of prematurity. 3. Participant characteristics: Preterm neonates with the gestational age of equal or less than 36 weeks or weight less than 2000g. 4. Key results: Dual strain probiotics significantly improved the daily weight gain of premature neonates. However, probiotics also decreased the risks of feeding intolerance and death during the hospital stay but these findings were not statistically significant.

•Preterm neonates fulfill one of the following criteria’s will be enrolled in the study.
•1- Gestational age of equal or less than 35weeks.
•2- Weight less than 2000g.

•Neonates have visible or physically detected malformation, birth weight less than 1000gr, severe birth asphyxia, seriously ill baby and parent who declined consent.

发起方

Professor Mansoor Aslamzai, MD