Effect of ultrafiltration on kidney functio

Phase 2

• Conditions: Condition 1: Chronic Ischemic Heart Disease. Condition 2: Acute Renal Failure with tubular necrosis.; Chronic ischaemic heart disease; Acute renal failure

• Registration Number: IRCT201103053438N3
• Lead Sponsor: rology and Nephrology Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients with coronary artery disease or vavular disease that come for elective first time on-pump operation will be recruited for the study.
Exclusion criteria:cre>1.5mg/dl, less than 3 days interval between angiography( dye contrast) till operation, urinary infection( presence of bacteria on urinary exam),Chronic lung disease(history of bronchodilator use or FEV1 less than 60%on spirometry), combine operation(coronary and valve) and urgent/emergency cases

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rinary NGAL. Timepoint: 2 TIMES2 TIMES(after urinary caheterizaion, and 2 hours after arrival at the intensive care unit). Method of measurement: ELISA.

Secondary Outcome Measures

Name	Time	Method
Serum creatinin. Timepoint: daily for 4 days. Method of measurement: laboratory equipment.;Intubation time. Timepoint: from entry to ICU till extubation. Method of measurement: hour.;Blood product requirement. Timepoint: during operation. Method of measurement: unit.;Chest tube drainage. Timepoint: from entry to ICU till chest tube removal. Method of measurement: ml.