The feasibility of preparing untreated esophageal adenocarcinoma endoscopic biopsies towards DNA/RNA samples suitable for next-generation sequencing.

Withdrawn

• Conditions: esophageal cancer; esophageal carcinoma; 10017990; 10017991; 10017998

• Registration Number: NL-OMON42638
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Studypopulation: patients who are diagnosed with esophageal adenocarcinoma and who undergo endoscopic ultrasonography.
written informed consent, patients fit for CROSS therapy and surgical resection.

Exclusion Criteria

incompetent, <18 year,.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The number of DNA and RNA samples suitable for next-generation sequencing.<br /><br>To assess this number, the following criteria have to be determined:<br /><br>- The amount of tumorsamples directly frozen after biopsy<br /><br>- The percentage of tumorcells in the biopsies<br /><br>- The amount of DNA in the biopsies<br /><br>- The amount of RNA in the biopsies</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>