nderstanding nutritional requirements of severe burn injury patients treated with a new skin substitute by directly measuring their individual energy expenditure.
Not Applicable
Recruiting
- Conditions
- Severe Burn injurySurgery - Other surgeryInjuries and Accidents - Burns
- Registration Number
- ACTRN12620000388910
- Lead Sponsor
- Royal Adelaide Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
This study aims to recruit adult patients (18 years or greater) with equal to or greater than 20% TBSA full-thickness burns requiring BTM application as part of their surgical management, admitted over a 12 month period
Exclusion Criteria
Severe head injury, age <18 years of age, known pre-existing inborn errors of metabolism, claustrophobia, inability to obtain informed consent (from patient or family members)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Resting energy expenditure (REE), measured via indirect calorimertry[Pre and post each surgical intervention, then weekly until discharge from hospital for the length of their inpatient stay. The number of measurements will vary per participant, depending on their length of stay which is dictated by their injury size and severity. There will be no further measurements or assessment once patients are discharged from their acute stay.]
- Secondary Outcome Measures
Name Time Method Difference between measured energy requirements from indirect calorimetry readings and standard predictor equations calculations used per current feeding protocols to determine accuracy of predictor equations.[Actual daily energy intake (calculated from food intake record) versus prescribed daily energy intake (as determined via indirect calorimetry), at each timepoint for measured REE (pre/post each surgical intervention (within 24 hours) and then weekly until discharge)]