Protocol to Obtain Blood Samples for Leukemia Research
Completed
- Conditions
- Chronic Lymphocytic Leukemia
- Interventions
- Other: No Intervention
- Registration Number
- NCT00889031
- Lead Sponsor
- Dartmouth-Hitchcock Medical Center
- Brief Summary
The purpose of this study is to collect a blood sample in patients with Chronic Lymphocytic Leukemia (CLL).
- Detailed Description
The blood sample will be used in the laboratory to perform studies focusing on Chronic Lymphocytic Leukemia (CLL).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 187
Inclusion Criteria
- Patients undergoing routine blood draws as part of their ongoing follow-up for Chronic Lymphocytic Leukemia (CLL) at the Norris Cotton Cancer Center of DHMC.
Exclusion Criteria
- Patients who have received cytotoxic drug, oral or intravenous steroid or targeted antibody therapy for CLL or other disease process within the past 6 months are excluded. Use of intravenous immunoglobulin (IVIg) is not a reason for exclusion.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description No Treatment No Intervention -
- Primary Outcome Measures
Name Time Method To determine the frequency with which CLL cells incubated ex vivo with vincristine undergo rapid interphase apoptosis. 2 Years
- Secondary Outcome Measures
Name Time Method To determine whether suppression or inhibition of BCL2 family members can acutely sensitize CLL cells to vincristine. 2 Years
Trial Locations
- Locations (1)
Dartmouth-Hitchcock Medical Center
🇺🇸Lebanon, New Hampshire, United States